Safety Assessment of Osthole Isolated from Prangos ferulacea: Acute and Subchronic Toxicities and Modulation of Cytochrome P450
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چکیده
منابع مشابه
antioxidant activity and safety assessment of tragopogon buphthalmoides hydroethanolic extract: acute and subchronic toxicities
tragopogon buphthalmoides (dc.) boiss, is widely used as a food additive with some imputed health effects in folk medicine of western iran. unfortunately, despite the prevalent medicinal uses of the plant, there are no reports on the toxic effects of t. buphthalmoides aerial parts. the present study evaluated the potential toxicity of dried hydroethanolic extract of the species in wistar rats. ...
متن کاملAntispasmodic effect of osthole and Prangos ferulacea extract on rat uterus smooth muscle motility
Several species of Prangos are traditionally used as emollient, carminative, tonic, anti-flatulent, anthelmintic and anti-thrombotic agents. Osthole, a coumarin isolated from Prangos, are believed to be responsible for some of its effects. In this research, relaxant effects of Prangos ferulacea extract and osthole on rat uterus contraction induced by KCl, acetylcholine (ACh), oxytocin and elect...
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کاتالیست یک سنتز جدید برای تیواترها توصیف شده است. واکنش الکل ها با آریل، هتروآریل و آلکیل تیو ل ها درحضور 1،3،5- تری آزو- 2،4،6- تری فسفرین-2،2،4،4،6،6 هگزاکلراید ((tapc به عنوان یک کاتالیست موُثر، بازده های خوب تا عالی از تیواترها را حاصل می کند. علاوه براین، واکنش تحت شرایط بدون فلز و بدون حلال پیش می رود، بنابراین یک مکمل جالب برای روش های شناخته شده سنتز تیواترها ارائه می دهد. یک مکانیسم ا...
15 صفحه اولAntispasmodic effects of Prangos ferulacea acetone extract and its main component osthole on ileum contraction
Prangos ferulacea is a plant found in the Mediterranean and Middle-east regions used as carminative, anti-flatulent, emollient and antibacterial herb. It is believed that the coumarins are responsible for some of known effects of Prangos. In this research the relaxant effects of P. ferulacea coumrin rich extract as well as osthole as its main prenylated coumarins were investigated on rat ileum ...
متن کاملAntioxidant activity and safety assessment of Tragopogon buphthalmoides hydroethanolic extract: Acute and subchronic toxicities
Tragopogon buphthalmoides (DC.) Boiss, is widely used as a food additive with some imputed health effects in folk medicine of western Iran. Unfortunately, despite the prevalent medicinal uses of the plant, there are no reports on the toxic effects of T. buphthalmoides aerial parts. The present study evaluated the potential toxicity of dried hydroethanolic extract of the species in wistar rats. ...
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ژورنال
عنوان ژورنال: Jundishapur Journal of Natural Pharmaceutical Products
سال: 2017
ISSN: 1735-7780,2228-7876
DOI: 10.5812/jjnpp.63764